Mucous membrane pemphigoid mmp is an autoimmune blistering disorder that is characterized by subepithelial bullae. Outcomes for mucous membrane pemphigoid depend on early. Mucous membrane pemphigoid is a rare autoimmune blistering disease primarily affecting mucosal surfaces. Report of two cases of mucous membrane pemphigoid with.
Bullous pemphigoid bp this strain is limited to the skin. A clinical formocular cicatricial pemphigoid ocpmay result in blindness if it involves the eyes. Mucous membrane pemphigoid mmp is an autoimmune blistering disorder that is characterized by subepithelial blisters. Like other forms of pemphigoid, the disorder is characterized by the formation of autoantibodies against structural proteins of the dermalepidermal junction. Other names include cicatricial pemphigoid, oral pemphigoid and ocular pemphigoid. Mucous membrane pemphigoid mmp this form of the disease affects the eyes, mouth, and throat. Levine early diagnosis and aggressive local and systemic therapy are critical to longterm visual outcome in cases of. Various basement membrane zone components have been identified as targets of autoantibodies in mmp and the disease is characterised by dermatologists based on these components. Scarring can result in severe structural changes to the vulva that may mimic the. Other diseases that produce the latter pattern linear band on. Mucous membrane pemphigoid genetic and rare diseases. Mmp is an uncommon blistering conditionwhich most frequently affects the lining of the mouth and gums.
Treatment strategies in mucous membrane pemphigoid article pdf available in therapeutics and clinical risk management 43. Various basement membrane zone components have been identified as targets of. Other mucosal sites that might be affected include the nasopharnyx, larynx, genitalia, rectum, and esophagus. Abstract lichen planus pemphigoides lpp is a rare autoimmune subepidermal blistering disease characterized by the coexistence of both lichen planus and bullous pemphigoid or mucous membrane pemph. To be a member of this group you must have a form of pemphigoid or an associated illness or be a supporter. Mucous membrane pemphigoid is a rare, chronic, blistering and scarring disease that affects the oral and ocular mucosa. Blistering and scarring may occur in the eyes, mouth, esophagus, larynx, and on the vulva.499 1355 417 562 1027 473 940 996 1498 1131 154 1303 14 1520 1408 73 259 1121 311 1376 1362 392 1227 3 757 253 358 227 656 568 719 341 1416 159 1034